| Background: Gridhrasi is a Vataja disorder derived from word ‘Gridh’ means vulture in Ayurveda, characterized by Ruka [1] (pain), Toda[1] (pricking sensation), Spandhan[1] (twitching),Stambha[1] (stiffness), and Gati Sanga(nighrah)[1][2][3][4] (difficulty in walking), with pain radiating from the Sphik (hip) to the Pada (foot) [1]. This clinical picture closely resembles sciatica, a common condition with a lifetime incidence of 10-40% [5]. A gap exists between the holistic diagnosis of Ayurveda's Nidana Panchaka and the structural findings of modern imaging like MRI. Aim: To conduct an observational study of Gridhrasi by evaluating it as sciatica through MRI of the lumbar spine. Methods: An observational study was conducted on patients presenting with classical symptoms of Gridhrasi. A detailed history, Nidana Panchaka evaluation, and clinical examination were performed. MRI scans of the lumbosacral spine were obtained to assess disc pathology and nerve compression. Results: A significant correlation was observed. A representative case of a 38-year-old male with Gridhrasi symptoms showed MRI findings of disc prolapse and radiculopathy at L4-L5 and L5-S1 levels, directly corresponding to the clinical presentation of sciatica. Conclusion: Gridhrasi is clinically comparable to sciatica. The integration of the Nidana Panchaka framework with modern MRI diagnostics provides a comprehensive, validated, and interdisciplinary approach to diagnosis, which can lead to more effective management strategies. |